The Tripartite Type III Secreton of Shigella flexneri Inserts Ipab and Ipac into Host Membranes
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The Tripartite Type III Secreton of Shigella flexneri Inserts Ipab and Ipac into Host Membranes
Bacterial type III secretion systems serve to translocate proteins into eukaryotic cells, requiring a secreton and a translocator for proteins to pass the bacterial and host membranes. We used the contact hemolytic activity of Shigella flexneri to investigate its putative translocator. Hemolysis was caused by formation of a 25-A pore within the red blood cell (RBC) membrane. Of the five protein...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1999
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.147.3.683